Cell Biology12 min

Mitosis

Every cell in your body came from a single fertilized egg through billions of rounds of mitosis. Learn how one cell becomes two — with perfect genetic fidelity — every time.

Chromatin
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Interphase
Cytokinesis

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Phase 1 of 6

Interphase

G₂ — Preparation

The cell has already duplicated its DNA and is growing in preparation for division. Chromosomes exist as loosely coiled chromatin — not yet condensed into visible X shapes.

  • DNA was fully replicated during S phase
  • Cell grows and synthesizes division proteins
  • Centrosomes have been duplicated

Why mitosis matters

Mitosis is the engine of growth, maintenance, and repair in multicellular life. Understanding it is foundational to understanding cancer, wound healing, and development.

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46 → 46

Mitosis is a copying process, not a halving one. Each daughter cell receives a complete copy of all 46 chromosomes — identical to the parent cell.

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1–2 Hours

A full mitotic cycle takes about 1–2 hours in human cells. Interphase can last 18–20 hours — the actual division is the quick part.

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Not Meiosis

Mitosis produces 2 identical diploid cells for growth and repair. Meiosis produces 4 genetically diverse haploid cells for sexual reproduction.

What happens when mitosis goes wrong?

Errors at the spindle assembly checkpoint can let chromosomes mis-segregate, giving daughter cells the wrong number — aneuploidy. When these errors affect genes that control the cell cycle, the result can be uncontrolled division: cancer. Many chemotherapy drugs disrupt spindle formation, freezing cells at metaphase so they self-destruct.

Quick recap

  1. 1
    Interphase (G₂)Cell grows; DNA already duplicated — ready to divide.
  2. 2
    ProphaseChromosomes condense; nuclear envelope breaks down; spindle forms.
  3. 3
    MetaphaseChromosomes line up at equator; spindle checkpoint fires.
  4. 4
    AnaphaseSister chromatids pulled to opposite poles; cell elongates.
  5. 5
    TelophaseNuclear envelopes reform; chromosomes decondense; furrow starts.
  6. 6
    CytokinesisCleavage furrow pinches cell in two → 2 identical daughter cells.